What current therapies target cancer cell metabolism and are they selective in not harming normal cells?

What current therapies target cancer cell metabolism and are they selective in not harming normal cells? Studying how cancer cells might arise and how they survive are important to developing effective treatments against them.

What current therapies target cancer cell metabolism and are they selective in not harming normal cells?

Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. cell, 144(5), 646-674.