What are the major variables, independent, and dependent.Are the measurements of major variables valid and reliable?

PICOT Question

Why was the study done (purpose)?

What was the study design?

What was the sampling technique?

What was the sample size?

What were the sample characteristics?

What are the major variables, independent, and dependent

Are the measurements of major variables valid and reliable?

How were the data analyzed? Were the statistics used appropriate?

Were there any untoward events during the conduct of the study?

How do the results fit with previous research in the area?

What does this research mean for clinical practice?